In 1998, needed to stop taking Buspar because the sound of dogs barking was driving me bonkers. Label: COUGH TABS FOR DOGS AND CATS- dextromethorphan hydrobromide and guaifenesin tablet. Chlorpheniramine maleate undergoes substantial first-pass effect. Veterinarians should be aware of phenylephrine's toxic potential in dogs since its use as a human decongestant has likely increased. Guaifenesin is relatively safe. Chlorpheniramine is a first-generation propylamine-derivative antihistamine. Do not use in pets that are allergic to it. Chlorpheniramine and its metabolites are primarily excreted in urine. Side effects are uncommon but may include vomiting, diarrhea, decreased appetite, sleepiness, drooling or anxiousness. If a negative reaction occurs, please call your veterinary office. The margin of safety is reported to be three times the normal dose and cardiovascular side-effects are rare. For dogs, toxicity symptoms will begin to be seen in doses of 40mg per pound of body weight. It comes in oral strips, lozenges, liquids or liquid-filled capsules and formulations often combine it with guaifenesin, acetaminophen, and pseudoephedrine. That means that if your dog were to eat one single capsule, it would have to weigh in at a mere 8.125 pounds to experience any possible toxic effects. Dextromethorphan is a non-addictive opioid that acts centrally by increasing the cough threshold, and is an ingredient that gets a lot of attention at the ASPCA Animal Poison Control Center during cold and flu season.. At high doses of ingestion, we can serotonin agonist activity. It is found in several over-the-counter cold remedies. Certain breeds and species are more sensitive, including cats and Japanese breeds of dogs (e.g., Akita, Shiba Inu). Label RSS; Share Bookmark & Share. Dextromethorphan is a drug used in many over-the-counter cough and cold medicines for its antitussive effects. - Answered by a verified Dog Veterinarian. ... we do prescribe guaifenesin to dogs, but at a dosage around one tablet for a dog your size ... it seems to be that toxicity, or at least adverse side effects, are seen with three or more times the recommended dosage. Drug Label Info. Dextromethorphan is given by mouth and is used off label to treat compulsive behaviors and occasionally used to treat cough. Phenylephrine is a sympathomimetic amine used orally in human medicine mainly as a decongestant. Oral absorption of chlorpheniramine in dogs is rapid and complete, reaching peak plasma concentrations in 30–60 min. View Package Photos. For owners of tiny dog breeds such as Chihuahuas or Pomeranians- beware. My dog ate some mucinex, what do I need to do? Mucinex Fast-Max Severe Congestion & Cough Liquid has three main active ingredients; both dextromethorphan and guaifenesin are used by Veterinarian in practice, but phenylephrine doesn’t have a therapeutic dose or toxic dose published for use in dogs. Signs of overdose include apneustic breathing, nystagmus, hypotension and increased muscle-rigidity. Objectives: Guaifenesin possesses expectorant, muscle relaxant, and anticonvulsive properties. The anxiety and depression I had and was trying to aleviate from a devorce was being linked to dogs barking and the sound of people eating. Serotonin syndrome in dogs is a potentially life-threatening condition caused by an increase of serotonin in the body from exposure to antidepressant medication. Overdose. Dextromethorphan is also a commo … Safety. I would bang on the window trying to stop the neibores dog until breaking the glass. Cough and cold medicines for its antitussive effects excreted in urine side-effects are rare dogs! 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